Azusa Pacific University Counter Signaling Biology Discussion
Imagine that you have engineered a set of genes, each encoding a protein with a pair of conflicting signal sequences that specify different compartments. If the genes were expressed in a cell, predict which signal would win out for the following combinations. Explain your reasoning.
- Signals for import into nucleus and import into ER.
- Signals for import into peroxisomes and import into ER.
for these two cases, I know that signals for ER works first.
but I don’t completely understand. I know that ER signal is at N-terminus and peroxisome is at C-terminus. and I don’t understand how it affects the answer. and also I don’t understand how signals for ER can work before fully synthesized while others can’t.
