Toxicology Worksheet
Exercise A – 3
Please answer the following questions for the rs4244285 genetic variant. Tip: go to https://www.ncbi.nlm.nih.gov/snp/ and enter “rs4244285” in the search field.
– In what gene does the rs4244285 variant exist?
– What is the wild-type allele? What is the variant allele?
– At what nucleotide position does the allele occur? At what codon
position does the allele occur?
– What is the type of genetic variant?
– Click on the “ALFA” tab
What is the frequency of the variant allele in the 1000Genomes Europe population?
What is the frequency of the variant allele in the 1000Genomes South Asian
population?
What is the frequency of the variant allele in the 1000Genomes Global
population?
